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Pathogenic Bacteria Group
2009-07-24 | A A A  [print][close]
Group leader:Shiyun Chen

   Quorum sensing (QS) is a communication system which involves the regulation of gene expression according to population densities. The laboratory is focused on the regulation and manipulation of QS of pathogenic bacteria using Gram negative Pseudomonas aeruginosa and Yersinia pseudotuberculosis as well as Gram positive Staphylococcus aureus as model organisms. Recently, it was determined that QS is important for normal biofilm development and research is underway to try to understand the mechanism of QS in biofilms at the molecular level. Other agents that have the potential to inhibit biofilm formation are also underinvestigation.The research utilizes cutting-edge technology such as proteomics and metabolomics.



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