Wuhan Institute of Virology (WIV), Chinese Academy of Sciences (CAS), was established in 1956 in Wuhan, China. It is a leading research institution that specializes in basic virology research and related technological innovations.

WIV focuses on both fundamental and applied research in virology, immunology, biotechnology, and other related fields. Its research areas include the detection, surveillance, and early warning of emerging and unknown pathogens; understanding the mechanisms of pathogenic viral infections; and developing new strategies and technologies for prevention and control of the diseases.

WIV is organized into three research centers that focus on pathogenesis, molecular virology, and antiviral research. It has established the State Key Laboratory of Virology and Biosafety in collaboration with Wuhan University. The institute also has various support departments, including the National Virus Resource Center (NVRC), designated by the Ministry of Science and Technology and the Ministry of Finance of China, the Core Facility Center, the Wuhan National Biosafety Laboratory, etc. The NVRC is recognized as the "National Culture Collection Center" by the National Health Commission of China. The Core Facility Center includes the Analysis and Testing Center, and the Experimental Animal Center. The Wuhan National Biosafety Laboratory is the first biosafety level-4 (BSL-4) laboratory to be built and operational in China. Additionally, Virologica Sinica, an English-language journal sponsored by WIV, is a core journal in biology and medicine, as well as an authoritative publication in virology in China. It recently achieved an impact factor of 4.3.