Jiaoyu DENG

Title: Principal Investigator E-mail: dengjy@wh.iov.cn


Deletion of nudB causes increased susceptibility to antifolates in Escherichia coli and Salmonella enterica. Antimicrob Agents Chemother, 2017 Feb 21.

Anti-folates potentiate bactericidal effects of other antimicrobial agents. J Antibiot (Tokyo). 2017 Mar; 70(3): 285-291.

Lysine acetylation regulates the activity of Escherichia coli pyridoxine 5'-phosphate oxidase. Acta Biochim Biophys Sin (Shanghai). 2016 Dec.

Mycobacterium tuberculosis arylamine N-acetyltransferase acetylates and thus inactivates para-aminosalicylic acid. Antimicrob Agents Chemother. 2016 Nov 21; 60(12): 7505-08.

Lysine acetylation regulates the activity of Escherichia coli S-adenosylmethionine synthase. Acta Biochim Biophys Sin (Shanghai). 2016 Aug; 48(8): 723-31.

Mycobacterium tuberculosis proteome microarray for global studies of protein function and immunogenicity. Cell Rep. 2014 Dec 24; 9(6): 2317-29.

Acetylome analysis reveals diverse functions of lysine acetylation in Mycobacterium tuberculosis. Mol Cell Proteomics. 2014 Dec; 13(12): 3352-66.

Acs is essential for propionate utilization in Escherichia coli. Biochem Biophys Res Commun. 2014 Jul 4; 449(3): 272-7.

Binding pocket alterations in dihydrofolate synthase confer resistance to para-aminosalicylic acid in clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2014; 58(3): 1479-87.

Reversibly acetylated lysine residues play important roles in the enzymatic activity of Escherichia coli N-hydroxyarylamine O-acetyltransferase. FEBS J. 2013 May; 280(9): 1966-79

Comparative analysis of mycobacterial NADH pyrophosphatase isoforms reveals a novel mechanism for isoniazid and ethionamide inactivation. Mol Microbiol. 2011 Dec; 82(6): 1375-91.

Mutually exclusive genotypes for pyrazinamide and 5-chloropyrazinamide resistance reveal a potential resistance-proofing strategy. Antimicrob Agents Chemother. 2010 Dec; 54(12): 5323-8.

CobB regulates Escherichia coli chemotaxis by deacetylating the response regulator CheY. Mol Microbiol. 2010 Jun 1; 76(5): 1162-74.

Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China. J Int Med Res. 2009 Sep-Oct; 37(5): 1430-5.