Research Progress

[08-10-2014]Research Advances on Viral Suppression of Innate Immunity

Recently, the research group led by Prof. Hualin Wang and Prof. Zhihong Hu from WIV has made important progress on viral immune evasion strategies, results of which have been published in Journal of Molecular Cell Biology (5-Yr impact factor: 8.953; Ning et al., 2014). Innate immune system is the first line of host defense against pathogen infections. Recent studies have suggested that mitochon...

[08-10-2014]An Authentic Mouse Model of Persistent Hepatitis C Virus Infection Becomes Available

Researchers from WIV and Institute of Biophysics, CAS, published a cover story on Cell Research, titled Persistent hepatitis C virus infections and hepatopathologicalmanifestations in immune-competent humanized mice, which reported the world's first immune-competent humanized mice that allow the natural infection of HCV.Almost 40 years ago, HCV was identified by researchers in NIH. There are ab...

[08-10-2014]New strategy for rapid drug susceptibility test

The research team led by Prof. Wei Hongping recently published three research papers in Journal of Clinical Microbiology on drug susceptibility tests using a new strategy named as gene-to-protein function (GPF) they proposed. “The most significant advantage of the GPF strategy is that it detects the drug susceptibility through the function of the proteins synthesized in vitro instead of the in...

[08-10-2014]Progress in molecular imaging

The research team led by Prof. Cui Zongqiang from Analytical Microbiology and Nano-biology Center in WIV, and Prof. Zhang Xian-En from IBP, recently developed novel far-red mNeptunebased bimolecular fluorescence complementation (BiFC) and trimolecular fluorescence complementation (TriFC) systems with excitation and emission above 600 nm in the ‘tissue optical window’ for imaging protein–prot...