In a recent study by the research group led by Prof. CUI Zongqiang in Wuhan Institute of Virology of the Chinese Academy of Sciences, using QD-based single-virus imaging, the scientists tracked the dynamic processes of HIV fusion and interactions with the cortical actin in resting CD4 T cells.
In a recent study by the research group led by Prof. XIAO Gengfu in Wuhan Institute of Virology of the Chinese Academy of Sciences, a comprehensive LASV GP interactome was characterized, and further study revealed that STT3B-dependent N-glycosylation was preferentially required by arenavirus GPs and critical for virus infectivity.
Zika virus (ZIKV), as a re-emerging viral pathogen, belongs to the Flaviviridae family including dengue virus (DENV), West Nile virus (WNV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), and tick borne encephalitic virus (TBEV). It can be transmitted by Aedes mosquitoe and cause severe neurological diseases including Guillain-Barre Syndrome (GBS) in the adult, and congenital Zika...
In a recent study, a simple and efficient mitochondria‐docking (Mito‐docking) method for PPI detection in vivo is developed by the research team led by Prof. HU Zhihong and Dr. WANG Manli. The strategy is to anchor a “bait” protein to mitochondrial outer membrane (MOM), and then trap the “prey” protein onto MOM. In this way, interacting signals are enriched to allow easy detection. This m...
