Research Progress

[17-06-2019]HRTV antagonizes IFN antiviral signaling by dampening both STAT2 and STAT1 activities

In a recent study, the research group led by Prof. WANG Hualin in Wuhan institute of Virology of the Chinese Academy of Sciences demonstrated that HRTV infection can block both type I and III IFN antiviral signaling. Furthermore, the mechanism underlying HRTV manipulation of type I and III IFN signaling was unraveled by detailed comparative studies in the context of HRTV infection and transient...

[06-06-2019]Scientists uncover the roadblocks to mammalian cell entry of baculovirus

In a recent study, the research groups led by Prof. WANG Hualin and Prof. HU Zhihong in Wuhan Institute of Virology of the Chinese Academy of Sciences uncovers the roadblocks encountered to mammalian cell entry of baculoviruses and presents mechanisms to overcome the roadblock.

[04-06-2019]Researchers suggest the F-Fc protein being a safe and effective RSV vaccine candidate

In a recent study, the research group led by Prof. XIAO Gengfu in Wuhan Institute of Virology of the Chinese Academy of Sciences developed a novel vaccine antigen, RSV glycoprotein F fused with an IgG Fc fragment (F-Fc).

[04-06-2019]Scientists provide the first demonstration of the NTPase/helicase-like activity encoded by EBOV

In a recent study, the research group led by Prof. ZHOU Xi in Wuhan Institute of Virology of the Chinese Academy of Sciences reported for the first time that the EBOV-encoded multifunctional protein VP35 has NTPase and helicase-like activities that can bind to NTPs, hydrolyze all types of NTPs and unwind RNA helices in an NTP-dependent manner.