Research Progress

[20-07-2020]Chinese Researchers Reveal an Arms Race between High-pathogenic Bunyavirus and Host Immunity

Scientists from Wuhan Institute of Virology (WIV) of the Chinese Academy of Sciences, recently uncovered an interesting interplay of SFTSV infection with the signaling mediated by RIG-I, a critical cellular PRR localized in cytosol (Figure 1). They found that RIG-I plays a major role in the cellular recognition of SFTSV and the host immune/inflammatory responses to SFTSV infection, but in turn,...