RgsA is a phylogenetically conserved small regulatory RNA (sRNA) in Pseudomonas species. This sRNA has been shown to be directly controlled by the major stationary phase and stress sigma factor σS (RpoS), and also indirectly regulated by the GacS/GacA two-component system. However, the role and the regulatory targets of this sRNA remain unclear. Here, the research group led by Professor Shiyun...
On June 2nd 2016, the study jointly developed by the research teams led by Professor Zongqiang Cui in WIV, Professor Xianen Zhang in Institute of Biophysics, CAS and Professor Zhike He in Wuhan University was published online by the ACS Nano journal. The research paper (DOI: 10.1021/acsnano.6b02462) first demonstrates the real-time imaging of single HIV-1 disassembly with multicolor viral parti...
Mycobacterium tuberculosis adopts various strategies to cope with oxidative stress during infection. Transcriptional regulators, including σ factors, make important contributions to this stress response, but how these proteins cooperate with each other is largely unknown. In the study (DOI: 10.1111/mmi.13449), the role of RbpA and its cooperation with σ factors in response to oxidative stress...
Human bocavirus (HBoV), a parvovirus, is a single-stranded DNA etiologic agent causing lower respiratory tract infections in young children worldwide. Nuclear factor kappa B (NF-κB) transcription factors play crucial roles in clearance of invading viruses through activation of many physiological processes. Previous investigation showed that HBoV infection could significantly upregulate the lev...
