Research Progress

[02-06-2016]Glycan-deficient PrP stimulates VEGFR2 signaling via glycosaminoglycan

One of the most common protein post-translational modifications is N-linked glycosylation. N-linked glycosylation is important in proper protein folding, transit to the cell surface and secretion, in a protein, as well as cell context dependent manner. The normal cellular prion protein, PrP, is a widely expressed, highly conserved, glycosylphosphatidylinositol (GPI)-anchored cell surface glyco...

[25-03-2016]Scientists from WIV have Isolated One Zika Virus Strain

By cooperation with Shenzhen Entry-Exit Inspection and Quarantine Bureau, scientists from WIV have isolated one Zika virus strain, which will assist scientists study the transmission pattern of the virus while provide a foundation for the invention of reagent and vaccine.

[23-01-2015]Chinese scientists construct the first M. tuberculosis proteome microarray

Tuberculosis, an ancient, yet re-emerging infectious disease, is responsible for more deaths than almost all other infectious diseases, and the vaccine, drugs and diagnostic tests currently in use are limiting the effectiveness of global efforts to prevent and control TB. The BCG vaccine, the only licensed TB vaccine, has now been in use for almost one hundred years; however, it provides only l...

[11-03-2016]New progress on self-assembly of ferritin nanoparticles

The self-assembly of nanoparticles into larger superstructures is a powerful strategy to develop novel functional nanomaterials, as these superstructures display collective properties that are different to those displayed by individual nanoparticles or bulk samples. However, there are increasing bottlenecks in terms of size control and multifunctionalization of nanoparticle assemblies.