Research Progress

[11-07-2012]WIV scientists reveal a potential new mechanism underlying HSV-2-mediated enhancement of HIV-1 mu...

Dr Qinxue Hu’s group in Wuhan Institute of Virology (WIV) reports a potential new mechanism underlying HSV-2-mediated enhancement of HIV-1 mucosal transmission (J Immunol, 2012 Jun 15;188(12):6247-57). The article has been selected and evaluated by Faculty of 1000. http://f1000.com/716997883 Epithelial cells are the main targets of HSV-2 while HIV-1 preferentially infects CD4+ T cells. It has ...

[16-05-2012]Professor Chunfu Zheng’s Lab has made significant headway in Herpes Simplex Virus Type 1

Dr. Chunfu Zheng’s Lab in Wuhan Institute of Virology has made significant headway in Herpes Simplex Virus Type 1 (HSV-1) research and published one article entitled “HSV-1 Tegument Protein US11 down-modulates RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5” in Journal of Virology in 2012. The interferon (IFN)-mediated antiviral response is a major defense of the host immune

[21-05-2012]Significant Progress Made by WIV in Research on Variant HBsAg

Recently, significant progress on variant Hepatitis B Surface Antigen (HBsAg)has been made by the research team led by Dr. Chen Xinwen at WIV . The research achievement was published in Journal of Virology (2012, 86(8), 4658-4669. doi: 10.1128 / JVI.06 353-11). Hepatitis B surface antige(HBsAg), the envelope proteins of hepatitis B virus (HBV), induce protective immune response. The region comp...

[06-12-2011]Professor Chunfu Zheng’s Lab has made significant headway in alphaherpesviruses

Dr. Chunfu Zheng’s Lab has made significant headway in alphaherpesviruses research and published three articles in Journal of Virology in 2011. One of Professor Chunfu Zheng’s articles titled “Varicella-Zoster Virus Immediate-Early Protein ORF61 Abrogates the IRF3-Mediated Innate Immune Response through Degradation of Activated IRF3” has been selected by the editors of the Journal of Virolo...