Atherosclerosis is a leading cause of death globally. Targeted imaging and therapeutics are desirable for the detection and treatment of the disease. Recently, the research group led by Prof. Zongqiang Cui in WIV developed trifunctional Simian virus 40 (SV40)-based nanoparticles for in vivo targeting and imaging of atherosclerotic plaques. These novel trifunctional SV40-based nanoparticles enca...
A new research report appearing on August 30th 2016 in Cell Reports dissects the cellular role of WhiB6, one of the WhiB redox sensor family proteins, in virulence and intracellular survival of pathogenic mycobacteria, according to researchers from the Center for Emerging Infectious Diseases, Wuhan Institute of Virology (WIV), Chinese Academy of Sciences (CAS).
RgsA is a phylogenetically conserved small regulatory RNA (sRNA) in Pseudomonas species. This sRNA has been shown to be directly controlled by the major stationary phase and stress sigma factor σS (RpoS), and also indirectly regulated by the GacS/GacA two-component system. However, the role and the regulatory targets of this sRNA remain unclear. Here, the research group led by Professor Shiyun...
On June 2nd 2016, the study jointly developed by the research teams led by Professor Zongqiang Cui in WIV, Professor Xianen Zhang in Institute of Biophysics, CAS and Professor Zhike He in Wuhan University was published online by the ACS Nano journal. The research paper (DOI: 10.1021/acsnano.6b02462) first demonstrates the real-time imaging of single HIV-1 disassembly with multicolor viral parti...
